Start Your Journey to Healing with the Patented APIC-A2M Regenerative Therapy


Introducing Alpha 2 Macroglobulin (A2M) for Osteoarthritic Joint and Back Pain

What does A2M regenerative therapy have to do with solving my joint or back pain?

Alpha-2-Macroglobulin (A2M) is different from other treatments. It is a naturally occurring molecule found in your blood, which when administered in concentrated doses, acts as a powerful protector against cartilage breakdown.

 A2M – A Miracle Molecule

A2M is a master protease inhibitor that exists in your blood. This special molecule works by removing the catabolic factors responsible for the chemical destruction of cartilage and the progression of OA. A2M accomplishes this by binding the proteases that degrade the cartilage cells and tissue and by filtering them out of the joint.

Early Treatment Equals Better Recovery

For patients suffering from joint or back pain, A2M therapy is an exciting advance in orthopedic science resulting from years of research. Early treatments of this miracle molecule can delay the need for more aggressive and costly procedures, including surgery.


Your current treatment may only be controlling your joint or back symptoms – not stopping or preventing them.

Though most patients find these types of treatments offer temporary relief they may not be eliminating the underlying source or arthritic joint and back pain.

With our patented APIC system, your A2M is concentrated up to 6X. This powerful serum can them protect and repair your damaged cartilage.

How A2M Works

For the majority of patients with pain, their arthritic joint or disc space houses more destructive enzymes than the body can handle. While the A2M Molecule is our body's own defense mechanism, it is unable to enter the joint or disc space in large enough quantities due to its large size and complex structure. As a result, it is necessary to inject additional concentrated A2M into the affected area to restore balance and pain relief.

An injection of concentrated A2M, derived from your own blood and placed directly into your joint or disc space can provide the necessary amount of A2M to bind and remove these destructive proteases.

A2M has two binding sites that capture proteases (E) like a venus flytrap.

Once captured, the bound A2M and proteases are elimated from the joint or disc space through your body's natural processes.

Find Greater Healing Power!

Reduce or Eliminate Inflammation and Pain. Prevent Further Breakdown of Tissue. Restore Joint Health.

Trust the Experts

trust the experts dr cert iconBeing informed is an important first step when choosing regenerative medicine therapies. As these new therapies are currently not covered by insurance, you should have the peace of mind that your therapy and care is being managed only by experts in pain management.

We offer a FREE consultation to see which regenerative medicine therapy may be right for you.

free consult only

Are you a Candidate?

candidate biomarker test iconAfter consultation, a simple FREE test may be performed by our doctors to help determine if you are a good candidate for our regenerative therapies. This test looks for a unique biomarker in your joint or disc space that indicates the presence of destructive enzymes.

What is the Biomarker?

Research has identified that the "pain protein" or "miracle molecule" – Fibronectin-Aggrecan Complex (FAC) – is associated with painful inflammation. Our doctors can test for a high presence of FAC and determine if you are an appropriate candidate for therapy.

Learn how regenerative therapies can alleviate your pain so you can enjoy an active life again.

Schedule your free consultation online or by calling:


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Our diverse physicians, nurse practitioners and physician assistants provides patients with the most comprehensive approach to pain management. We have convenient locations across Wisconsin and Minnesota including Appleton, Chaska, Green Bay, Kenosha, Madison, Mankato, Milwaukee, Racine, Sheboygan, Stevens Point, Waukesha, Wausau and many more.

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